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Liver Arginase 抗体 (N-Term)

ARG1 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, Pig, 马, 山羊, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782309
发货至: 中国
  • 抗原 See all Liver Arginase (ARG1) 抗体
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    抗原表位
    • 24
    • 19
    • 16
    • 12
    • 12
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 大鼠, 小鼠, 兔, Cow, 犬, Pig, 马, 山羊, 豚鼠, Saccharomyces cerevisiae
    宿主
    • 108
    • 27
    • 5
    • 3
    • 2
    克隆类型
    • 109
    • 36
    多克隆
    标记
    • 80
    • 13
    • 11
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Liver Arginase antibody is un-conjugated
    应用范围
    • 95
    • 58
    • 34
    • 30
    • 20
    • 19
    • 14
    • 13
    • 12
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    SAKSRTIGII GAPFSKGQPR GGVEEGPTVL RKAGLLEKLK EQECDVKDYG
    交叉反应
    牛, 人, 小鼠, 猪, 兔, 大鼠
    预测反应
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%
    产品特性
    This is a rabbit polyclonal antibody against ARG1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ARG1
    Top Product
    Discover our top product ARG1 Primary Antibody
  • 应用备注
    WB Suggested Anti-ARG1 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: Human Liver.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 322 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kitowska, Zakrzewicz, Königshoff, Chrobak, Grimminger, Seeger, Bulau, Eickelberg: "Functional role and species-specific contribution of arginases in pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 1, pp. L34-45, (2008) (PubMed).

  • 抗原
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    别名
    Arginase-1 (ARG1 产品)
    别名
    SI:zC146F4.4 (novel protein with NUDIX domain) antibody, si:ch211-146f4.3 antibody, argi1 antibody, AI antibody, AI256583 antibody, Arg-1 antibody, PGIF antibody, arginase 1 antibody, arginase antibody, Arginase-1 antibody, arginase, liver antibody, L-arginase antibody, arg1 antibody, PGTG_16455 antibody, argi1 antibody, ARG1 antibody, Arg1 antibody
    背景
    Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: RPA3, RPA2, RPA1, SUZ12, EZH2, BMI1, ALDH4A1, ESR1, RAD21, UBC, UCHL5, ATG101, USP53, FLOT1, NOS1, ARG2,
    Protein Size: 322
    分子量
    35 kDa
    基因ID
    383
    NCBI登录号
    NM_000045, NP_000036
    UniProt
    P05089
    途径
    Cellular Response to Molecule of Bacterial Origin
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