RORA 抗体 (N-Term)
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- 抗原 See all RORA 抗体
- RORA (RAR-Related Orphan Receptor A (RORA))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RORA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ARKSEPPAPV RRQSYSSTSR GISVTKKTHT SQIEIIPCKI CGDKSSGIHY
- 预测反应
- Cow: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RORA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RORA
- Top Product
- Discover our top product RORA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 523 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RORA (RAR-Related Orphan Receptor A (RORA))
- 别名
- RORA (RORA 产品)
- 背景
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The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZRA, RZR-ALPHA
Protein Interaction Partner: GFAP, NSD1, NCOA1, PSMC5, SMARCD3, PTBP1, VPRBP, UBC, EZH2, DDB1, LMO3, NR0B1, ZXDC, PNRC2, COPS5, PNRC1, EIF3I, PROX1, LRIF1, RUVBL1, CEBPB, NCOA2, MED1, EP300, RORA, MYOD1, NME2, NME1,
Protein Size: 523 - 分子量
- 59 kDa
- 基因ID
- 6095
- NCBI登录号
- NM_134261, NP_599023
- UniProt
- B6ZGS4
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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