NR5A1 抗体 (Middle Region)
-
- 抗原 See all NR5A1 抗体
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
-
抗原表位
- Middle Region
-
适用
- 人, 大鼠, 豚鼠, 马, 兔, 犬, Cow, 绵羊, Pig
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This NR5A1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- SLHGPEPKGL AAGPPAGPLG DFGAPALPMA VPGAHGPLAG YLYPAFPGRA
- 预测反应
- Cow: 79%, Dog: 86%, Guinea Pig: 91%, Horse: 86%, Human: 100%, Pig: 92%, Rabbit: 79%, Rat: 86%, Sheep: 79%
- 产品特性
- This is a rabbit polyclonal antibody against NR5A1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NR5A1
- Top Product
- Discover our top product NR5A1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 461 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
SMAD3 inhibits SF-1-dependent activation of the CYP17 promoter in H295R cells." in: Molecular and cellular biochemistry, Vol. 307, Issue 1-2, pp. 65-71, (2007) (PubMed).
: "
-
SMAD3 inhibits SF-1-dependent activation of the CYP17 promoter in H295R cells." in: Molecular and cellular biochemistry, Vol. 307, Issue 1-2, pp. 65-71, (2007) (PubMed).
-
- 抗原
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
- 别名
- NR5A1 (NR5A1 产品)
- 别名
- AD4BP antibody, ELP antibody, FTZ1 antibody, FTZF1 antibody, POF7 antibody, SF-1 antibody, SF1 antibody, SPGF8 antibody, SRXY3 antibody, Ad4BP antibody, ELP-3 antibody, Ftz-F1 antibody, Ftzf1 antibody, Ad4BP/SF-1 antibody, Ad4bp antibody, Sf-1 antibody, NR5A1 antibody, sf-1 antibody, elp antibody, sf1 antibody, ftz1 antibody, ad4bp antibody, ftzf1 antibody, SF-1/Ad4BP antibody, SI:zC167P9.2 antibody, ff1d antibody, nr5a2l antibody, nuclear receptor subfamily 5 group A member 1 antibody, nuclear receptor subfamily 5, group A, member 1 antibody, nuclear receptor subfamily 5 group A member 1 L homeolog antibody, nuclear receptor subfamily 6 group A member 1 antibody, nuclear receptor subfamily 5, group A, member 1b antibody, NR5A1 antibody, Nr5a1 antibody, nr5a1.L antibody, nr5a1 antibody, NR6A1 antibody, nr5a1b antibody
- 背景
-
NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AD4BP, ELP, FTZ1, FTZF1, SF-1, SF1, POF7, SPGF8, SRXY3
Protein Interaction Partner: NCK2, NR0B1, RAD54L2, THOC2, ALYREF, EIF4A3, DDX39B, UBC, BARD1, ELAVL1, TCF7L2, CTNNB1, CREBBP, CXXC1, PNRC2, SOX8, PIAS1, ZNF653, TRERF1, EDF1, GATA4, GTF2B, SOX2, SOX9, TBX19, NCOA1, NRIP1, PITX1, SMARCD3, PROX1, AR, SP1, NFYA, MAPK1, JUN, NFKB2,
Protein Size: 461 - 分子量
- 52 kDa
- 基因ID
- 2516
- NCBI登录号
- NM_004959, NP_004950
- UniProt
- Q13285
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Maintenance of Protein Location
-