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- 抗原 See all TIM3 (TIM 3) 抗体
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
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抗原表位
- N-Term
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适用
- 人, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIM3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MFSHLPFDCV LLLLLLLLTR SSEVEYRAEV GQNAYLPCFY TPAAPGNLVP
- 预测反应
- Dog: 79%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against HAVCR2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HAVCR2
- Top Product
- Discover our top product TIM 3 Primary Antibody
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anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (Internal Region) antibody
Verified TIM 3 适用: 人 FACS, WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibodyTIM 3 适用: 人 ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal TIM3-3113 unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 167-194) antibodyTIM 3 适用: 人 WB 宿主: 兔 Polyclonal RB41963 unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibodyTIM 3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibodyTIM 3 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 7C8A7 unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 224-301) antibodyTIM 3 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2A7A6 unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) antibodyTIM 3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 224-301) antibodyTIM 3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5A7D12 unconjugated
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) antibodyTIM 3 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-366R unconjugated Recombinant Antibody
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibodyTIM 3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 301 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 别名
- HAVCR2 (TIM 3 产品)
- 物质类
- Virus
- 背景
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HAVCR2 regulates macrophage activation. HAVCR2 inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. HAVCR2 may be also involved in T-cell homing. HAVCR2 is the receptor for LGALS9.CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ14428, KIM-3, TIM3, TIMD3, Tim-3, TIMD-3, HAVcr-2
Protein Interaction Partner: BAG6, LCK, APP, HAVCR2,
Protein Size: 301 - 分子量
- 33 kDa
- 基因ID
- 84868
- NCBI登录号
- NM_032782, NP_116171
- UniProt
- Q8TDQ0
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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