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TAPBP 抗体 (C-Term)

TAPBP 适用: 人, 绵羊, Cow, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782218
发货至: 中国
  • 抗原 See all TAPBP 抗体
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    抗原表位
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 36
    • 9
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 绵羊, Cow, Pig
    宿主
    • 36
    克隆类型
    • 36
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TAPBP antibody is un-conjugated
    应用范围
    • 29
    • 14
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    GEAPPELLCL VSHFYPSGGL EVEWELRGGP GGRSQKAEGQ RWLSALRHHS
    预测反应
    Cow: 86%, Human: 100%, Pig: 86%, Sheep: 86%
    产品特性
    This is a rabbit polyclonal antibody against TAPBP. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human TAPBP
    Top Product
    Discover our top product TAPBP Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 448 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    别名
    TAPBP (TAPBP 产品)
    别名
    SI:dZ179B20.1 antibody, SI:dZ179B20.3 antibody, SI:dZ179B20.7 antibody, mhc1uda antibody, mhc1ufa antibody, tpsn antibody, zgc:109814 antibody, tapbp antibody, TAPBP antibody, D17Wsu91e antibody, TPN antibody, NGS17 antibody, TAPA antibody, TPSN antibody, TAP binding protein (tapasin), tandem duplicate 1 antibody, TAP binding protein antibody, tapbp.1 antibody, tapbp antibody, TAPBP antibody, Tapbp antibody
    背景
    TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
    Alias Symbols: NGS17, TAPA, TPN, TPSN
    Protein Interaction Partner: UBC, PDIA3, Tap2, ELAVL1, US3, TAP1, B2M, COPG1, COPG2, COPB1, HLA-C, HLA-A, CALR,
    Protein Size: 448
    分子量
    46 kDa
    基因ID
    6892
    NCBI登录号
    NM_003190, NP_003181
    UniProt
    O15533
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