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Indian Hedgehog 抗体 (N-Term)

IHH 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 斑马鱼, Cow, 山羊, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782160
发货至: 中国
  • 抗原 See all Indian Hedgehog (IHH) 抗体
    Indian Hedgehog (IHH)
    抗原表位
    • 15
    • 10
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 斑马鱼, Cow, 山羊, 马
    宿主
    • 69
    • 4
    • 4
    克隆类型
    • 69
    • 8
    多克隆
    标记
    • 33
    • 8
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Indian Hedgehog antibody is un-conjugated
    应用范围
    • 48
    • 37
    • 26
    • 13
    • 13
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    AAWGCGPGRV VGSRRRPPRK LVPLAYKQFS PNVPEKTLGA SGRYEGKIAR
    预测反应
    Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against IHH. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human IHH
    Top Product
    Discover our top product IHH Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 411 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mirza, Qiao, Tateyama, Miyamoto, Xiuli, Seo: "3?-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species." in: Journal of bone and mineral metabolism, Vol. 30, Issue 2, pp. 144-53, (2012) (PubMed).

  • 抗原
    Indian Hedgehog (IHH)
    别名
    IHH (IHH 产品)
    别名
    BDA1 antibody, HHG2 antibody, X-hh antibody, Xbhh antibody, bhh antibody, bhh-a antibody, IHH antibody, ehh antibody, zgc:113262 antibody, indian hedgehog antibody, Indian hedgehog antibody, indian hedgehog S homeolog antibody, Indian hedgehog homolog b antibody, IHH antibody, Ihh antibody, ihh.S antibody, ihhb antibody
    背景
    IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP).
    Alias Symbols: BDA1, HHG2
    Protein Interaction Partner: RHOD, HHIP, PTCH2, PTCH1,
    Protein Size: 411
    分子量
    45 kDa
    基因ID
    3549
    NCBI登录号
    NM_002181, NP_002172
    UniProt
    Q14623
    途径
    Hedgehog Signaling
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