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GNS 抗体 (C-Term)

Name: GNS 抗体 (C-Term)
SKU: ABIN2782155
Availability: OutOfStock

GNS 适用: 人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 兔, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-GNS Antibody Titration: 0. (GNS 抗体 (C-Term))

Rabbit Anti-GNS Antibody Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Cytoplasm in Kupffer cells in sinusoids Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (GNS 抗体 (C-Term))

IHC

Rabbit Anti-GNS Antibody Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (GNS 抗体 (C-Term))

IHC

3 images

产品编号 ABIN2782155

发货至: 中国

Datasheet as PDF

抗原 See all GNS 抗体

GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
抗原表位
15

3

3

1

1

1

1

1

1

1

1

1
C-Term
适用
32

7

5

2

2

2

2

2

2

2

1

1
人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 兔, 犬, 斑马鱼
宿主
29

2

1
兔
Compatible Secondaries
克隆类型
32
多克隆
标记
18

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This GNS antibody is un-conjugated
应用范围
16

13

13

10

5

5

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

PILRGASNLT WRSDVLVEYQ GEGRNVTDPT CPSLSPGVSQ CFPDCVCEDA

预测反应

Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

产品特性

This is a rabbit polyclonal antibody against GNS. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human GNS

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anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 293-552) antibody
GNS 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 1-552) antibody
GNS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 293-552) antibody
GNS 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 283-313) antibody
GNS 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19341 unconjugated

anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) antibody
GNS 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 1-552) antibody
GNS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 312-361) antibody
GNS 适用: 人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 兔, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 398-447) antibody
GNS 适用: 人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (C-Term) antibody
GNS 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 238-355) antibody
GNS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 552 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

别名

GNS (GNS 产品)

别名

G6S antibody, 2610016K11Rik antibody, AU042285 antibody, C87209 antibody, N28088 antibody, NV14559 antibody, N-acetylglucosamine-6-sulfatase antibody, zgc:114066 antibody, gns antibody, wu:fi20h10 antibody, zgc:55370 antibody, glucosamine (N-acetyl)-6-sulfatase antibody, glucosamine (N-acetyl)-6-sulfatase S homeolog antibody, glucosamine (N-acetyl)-6-sulfatase a antibody, N-acetylglucosamine-6-sulfatase antibody, glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b antibody, GNS antibody, Gns antibody, gns.S antibody, gns antibody, gnsa antibody, CpipJ_CPIJ000745 antibody, Sros_7372 antibody, VDBG_04409 antibody, Halhy_3165 antibody, gnsb antibody

背景

GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparin sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder ucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
Alias Symbols: G6S, MGC21274
Protein Interaction Partner: LDHAL6B, BCCIP, UBFD1, CNDP2, SCLY, C11orf58, GDA, KYNU, RPS6KA1, PEPD, MVD, GLS, GLA, GBP2, G6PD, EIF5A, CASP7, CAPN1, FBXO6, UBC,
Protein Size: 552

分子量

62 kDa

基因ID

2799

NCBI登录号

NM_002076, NP_002067

UniProt

P15586

途径

Glycosaminoglycan Metabolic Process