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HBEGF 抗体 (N-Term)

HBEGF 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782149
发货至: 中国
  • 抗原 See all HBEGF 抗体
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    抗原表位
    • 15
    • 15
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 兔
    宿主
    • 68
    • 9
    克隆类型
    • 66
    • 10
    • 1
    多克隆
    标记
    • 25
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HBEGF antibody is un-conjugated
    应用范围
    • 33
    • 29
    • 26
    • 15
    • 13
    • 10
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    FLAAVLSALV TGESLERLRR GLAAGTSNPD PPTVSTDQLL PLGGGRDRKV
    预测反应
    Cow: 100%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against HBEGF. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human HBEGF
    Top Product
    Discover our top product HBEGF Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    别名
    HBEGF (HBEGF 产品)
    别名
    hbegf antibody, zgc:165443 antibody, HBEGF antibody, zgc:175091 antibody, DTR antibody, DTS antibody, DTSF antibody, HEGFL antibody, Dtr antibody, GFHB antibody, Hb-egf antibody, Hegfl antibody, AW047313 antibody, Dts antibody, HB-EGF antibody, heparin-binding EGF-like growth factor b antibody, heparin binding EGF like growth factor antibody, Heparin-binding EGF-like growth factor antibody, heparin-binding EGF-like growth factor a antibody, heparin-binding EGF-like growth factor antibody, hbegfb antibody, HBEGF antibody, hbegf antibody, hbegfa antibody, Hbegf antibody
    背景
    HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.
    Alias Symbols: DTR, DTS, DTSF, HEGFL
    Protein Interaction Partner: Bag1, BCL6, ZBTB16, CD82, NRD1, LTBP3, ERBB4, MMP7, CD9, FBLN1, EGFR, HBEGF, CD44,
    Protein Size: 208
    分子量
    22 kDa
    基因ID
    1839
    NCBI登录号
    NM_001945, NP_001936
    UniProt
    Q99075
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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