COX10 抗体 (Middle Region)
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- 抗原 See all COX10 抗体
- COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COX10 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- APGPFDWPCF LLTSVGTGLA SCAANSINQF FEVPFDSNMN RTKNRPLVRG
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against COX10. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human COX10
- Top Product
- Discover our top product COX10 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 443 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
- 别名
- COX10 (COX10 产品)
- 别名
- 2410004F01Rik antibody, AU042636 antibody, im:7145568 antibody, im:7157205 antibody, wu:fb18a03 antibody, F4I1.50 antibody, F4I1_50 antibody, cytochrome c oxidase 10 antibody, Cox10 antibody, cytochrome c oxidase assembly protein 10 antibody, COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor antibody, COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor L homeolog antibody, COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor antibody, cytochrome c oxidase 10 antibody, protoheme IX farnesyltransferase, mitochondrial antibody, Cox10 antibody, cox10 antibody, cox10.L antibody, COX10 antibody, LOC100732273 antibody
- 背景
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Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. COX10 is heme A: farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Size: 443 - 分子量
- 49 kDa
- 基因ID
- 1352
- NCBI登录号
- NM_001303, NP_001294
- UniProt
- Q12887
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