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PARL 抗体 (N-Term)

Name: PARL 抗体 (N-Term)
SKU: ABIN2782038
Availability: OutOfStock

PARL 适用: 人, 小鼠, 大鼠, 犬, Pig, 兔, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-PARL Antibody Titration: 0. (PARL 抗体 (N-Term))

Immunohistochemistry (IHC) image for anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibody (ABIN2782038) (PARL 抗体 (N-Term))

IHC

IHC

Host: Rabbit Target Name: PARL Sample Tissue: Human Jurkat Antibody Dilution: 1. (PARL 抗体 (N-Term))

Rabbit Anti-PARL Antibody Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue Observed Staining: Cytoplasmic in alveolar type I cells Primary Antibody Concentration: 1:100 Other Working Concentrations: 1/600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (PARL 抗体 (N-Term))

IHC

5 images

(1 reference)

产品编号 ABIN2782038

发货至: 中国

Datasheet as PDF

抗原 See all PARL 抗体

PARL (Presenilin Associated, Rhomboid-Like (PARL))
抗原表位
4

2

2

2

1

1

1

1

1
N-Term
适用
21

9

8

3

2

1

1

1

1

1

1

1
人, 小鼠, 大鼠, 犬, Pig, 兔, 马, Cow, 豚鼠
宿主
17

3

2
兔
Compatible Secondaries
克隆类型
19

3
多克隆
标记
15

1

1

1

1

1

1

1
This PARL antibody is un-conjugated
应用范围
11

9

7

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

SLIKPLFFTV GFTGCAFGSA AIWQYESLKS RVQSYFDGIK ADWLDSIRPQ

预测反应

Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%,

产品特性

This is a rabbit polyclonal antibody against PARL. It was validated on Western Blot and immunohistochemistry.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human PARL
anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibody
PARL 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 1-170) antibody
PARL 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 97-146) antibody
PARL 适用: 人, 小鼠, 大鼠, 犬, Pig, 兔, 马, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 112-167) antibody
PARL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8C4B2 unconjugated

anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 1-170) antibody
PARL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 2-100) antibody
PARL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4F4 unconjugated

anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibody
PARL 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated

anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 40-90), (N-Term) antibody
PARL 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Presenilin Associated, Rhomboid-Like (PARL) (C-Term) antibody
PARL 适用: 人, 小鼠, 大鼠, 小鸡, 灵长类 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated

anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibody
PARL 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 329 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Yoshioka, Katsu, Sakata, Okami, Wakai, Kinouchi, Chan: "The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 11, pp. 1658-65, (2013) (PubMed).
抗原

PARL (Presenilin Associated, Rhomboid-Like (PARL))

别名

PARL (PARL 产品)

别名

PSARL antibody, PSARL1 antibody, PSENIP2 antibody, RHBDS1 antibody, D16Ertd607e antibody, PRO2207 antibody, Psarl antibody, parl antibody, zgc:112986 antibody, presenilin associated rhomboid like antibody, presenilin associated, rhomboid-like antibody, presenilin associated, rhomboid-like a antibody, PARL antibody, Parl antibody, parla antibody

背景

PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: PRO2207, PSARL, PSARL1, PSENIP2, RHBDS1
Protein Interaction Partner: UBC, PINK1,
Protein Size: 329

分子量

36 kDa

基因ID

55486

NCBI登录号

NM_001037639, NP_001032728

途径

Autophagy