LECT1 抗体 (N-Term)
-
- 抗原 See all LECT1 抗体
- LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))
-
抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This LECT1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- AIAVNDFQNG ITGIRFAGGE KCYIKAQVKA RIPEVGAVTK QSISSKLEGK
- 预测反应
- Cow: 100%, Dog: 92%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against LECT1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LECT1
- Top Product
- Discover our top product LECT1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 334 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))
- 别名
- LECT1 (LECT1 产品)
- 别名
- chm1 antibody, chm-i antibody, bricd3 antibody, MGC53801 antibody, MGC82444 antibody, chondromodulin-I antibody, Lect1 antibody, BRICD3 antibody, CHM-I antibody, CHM1 antibody, MYETS1 antibody, Bricd3 antibody, ChM-I antibody, Chm-1 antibody, chondromodulin L homeolog antibody, leukocyte cell derived chemotaxin 1 antibody, chondromodulin antibody, cnmd.L antibody, lect1 antibody, CNMD antibody, cnmd antibody, Cnmd antibody
- 背景
-
LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The mature protein promotes chondrocyte growth and inhibits angiogenesis. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: BRICD3, CHM-I, CHM1, MYETS1
Protein Interaction Partner: MYC, APOA1, FURIN,
Protein Size: 334 - 分子量
- 37 kDa
- 基因ID
- 11061
- NCBI登录号
- NM_007015, NP_008946
- UniProt
- O75829
-