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Osteoactivin 抗体 (N-Term)

GPNMB 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2781893
发货至: 中国
  • 抗原 See all Osteoactivin (GPNMB) 抗体
    Osteoactivin (GPNMB)
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 58
    • 24
    • 23
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 兔
    宿主
    • 45
    • 14
    克隆类型
    • 46
    • 13
    多克隆
    标记
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Osteoactivin antibody is un-conjugated
    应用范围
    • 46
    • 22
    • 13
    • 13
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    DENDWNEKLY PVWKRGDMRW KNSWKGGRVQ AVLTSDSPAL VGSNITFAVN
    特异性
    100 % homologous to both isoforms of hGPNMB
    预测反应
    Cow: 100%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against GPNMB. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB
    Top Product
    Discover our top product GPNMB Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 560 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Osteoactivin (GPNMB)
    别名
    GPNMB (GPNMB 产品)
    别名
    HGFIN antibody, NMB antibody, DC-HIL antibody, Dchil antibody, ipd antibody, glycoprotein nmb antibody, glycoprotein (transmembrane) nmb antibody, glycoprotein nmb L homeolog antibody, Gpnmb antibody, GPNMB antibody, gpnmb.L antibody
    背景
    GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: HGFIN, NMB
    Protein Interaction Partner: UBC, SMAD4, ITSN2,
    Protein Size: 560
    分子量
    63 kDa
    基因ID
    10457
    NCBI登录号
    NM_002510, NP_002501
    UniProt
    Q14956
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