LCLAT1 抗体 (Middle Region)
(1 reference)-
- 抗原 See all LCLAT1 抗体
- LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
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抗原表位
- Middle Region
- 适用
- 小鼠, 人, 大鼠, 兔, 马, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LCLAT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE
- 预测反应
- Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%
- 产品特性
- This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human LYCAT
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anti-Lysocardiolipin Acyltransferase 1 (LCLAT1) (AA 296-324) antibody
LCLAT1 适用: 小鼠, 人 WB, IHC (p) 宿主: 兔 Polyclonal RB27045 unconjugated
anti-Lysocardiolipin Acyltransferase 1 (LCLAT1) (AA 261-360) antibodyLCLAT1 适用: 小鼠, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysocardiolipin Acyltransferase 1 (LCLAT1) (C-Term) antibodyLCLAT1 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysocardiolipin Acyltransferase 1 (LCLAT1) antibodyLCLAT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysocardiolipin Acyltransferase 1 (LCLAT1) (AA 296-324), (C-Term) antibodyLCLAT1 适用: 小鼠, 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 376 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." in: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).
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: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." in: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).
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- 抗原
- LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
- 别名
- LYCAT (LCLAT1 产品)
- 背景
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LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
Protein Interaction Partner: LNX1, GOPC, RNF2, UBC, ELAVL1,
Protein Size: 376 - 分子量
- 44 kDa
- 基因ID
- 253558
- NCBI登录号
- NM_001002257, NP_001002257
- UniProt
- Q6UWP7
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