FGG 抗体 (Middle Region)
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- 抗原 See all FGG 抗体
- FGG (Fibrinogen gamma Chain (FGG))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGG antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- GWTVFQKRLD GSVDFKKNWI QYKEGFGHLS PTGTTEFWLG NEKIHLISTQ
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%
- 产品特性
- This is a rabbit polyclonal antibody against FGG. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FGG
- Top Product
- Discover our top product FGG Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 437 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- FGG (Fibrinogen gamma Chain (FGG))
- 别名
- FGG (FGG 产品)
- 别名
- FXII antibody, HAF antibody, 3010002H13Rik antibody, AI256424 antibody, fibrinogen antibody, FGG antibody, LOC100220680 antibody, fb60h05 antibody, fb62e01 antibody, wu:fb60h05 antibody, wu:fb62e01 antibody, zgc:56023 antibody, fibrinogen gamma chain antibody, coagulation factor XII (Hageman factor) antibody, fibrinogen gamma chain L homeolog antibody, FGG antibody, F12 antibody, fgg antibody, Fgg antibody, fgg.L antibody, CpipJ_CPIJ006387 antibody, CpipJ_CPIJ010087 antibody
- 背景
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FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: -
Protein Interaction Partner: SUMO2, ASB12, ASB7, ASB6, FN1, VKORC1, KHDRBS2, SERPINA5, VTN, ITGB3, ICAM1, FGG, FGB, FGA, F13B, F13A1, ITGAM,
Protein Size: 437 - 分子量
- 46 kDa
- 基因ID
- 2266
- NCBI登录号
- NM_000509, NP_000500
- UniProt
- P02679
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