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- 抗原 See all G6PC 抗体
- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This G6PC antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- NLVFKWILFG QRPYWWVLDT DYYSNTSVPL IKQFPVTCET GPGSPSGHAM
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against G6PC. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human G6PC
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 357 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and may contain up to 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis." in: PLoS ONE, Vol. 8, Issue 7, pp. e70309, (2013) (PubMed).
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Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis." in: PLoS ONE, Vol. 8, Issue 7, pp. e70309, (2013) (PubMed).
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- 抗原
- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
- 别名
- G6PC (G6PC 产品)
- 别名
- AW107337 antibody, G6Pase antibody, G6pt antibody, Glc-6-Pase antibody, G6PC1 antibody, G6PT antibody, GSD1 antibody, GSD1a antibody, G-6-Pase antibody, glucose-6-phosphatase, catalytic antibody, glucose-6-phosphatase catalytic subunit antibody, glucose-6-phosphatase, catalytic subunit antibody, G6pc antibody, G6PC antibody
- 背景
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G6PC hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: G6PT, GSD1a, MGC163350, GSD1, G6PC1
Protein Interaction Partner: NSL1, SNX13, CDH16, FOXO1,
Protein Size: 357 - 分子量
- 40 kDa
- 基因ID
- 2538
- NCBI登录号
- NM_000151, NP_000142
- UniProt
- P35575
- 途径
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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