EPOR 抗体 (N-Term)
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- 抗原 See all EPOR 抗体
- EPOR (Erythropoietin Receptor (EPOR))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPOR antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DHLGASLWPQ VGSLCLLLAG AAWAPPPNLP DPKFESKAAL LAARGPEELL
- 预测反应
- Cow: 85%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against EPOR. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EPOR
- Top Product
- Discover our top product EPOR Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 508 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- EPOR (Erythropoietin Receptor (EPOR))
- 别名
- EPOR (EPOR 产品)
- 别名
- EPOR antibody, epor antibody, EPO-R antibody, erythropoietin receptor antibody, erythropoietin receptor L homeolog antibody, EPOR antibody, epor antibody, Epor antibody, epor.L antibody
- 背景
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The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC138358, EPO-R
Protein Interaction Partner: PIK3R1, SRC, MST1R, JAK2, SH2B2, STAT5A, CBL, CRKL, GRB2, UBC, SOCS2, PLCG1, INPP5D, CISH, NOSIP, ATXN2L, GAB2, GAB1, GRAP, STAT5B, SOCS3, MAPK3, IRS2, SHC1, PLCG2, SYK, KITLG, GNB2L1, MAPK1, PTPN6, PTPN11, KLK3, LYN, KIT, VAV1, GNAI1, CSF2RB, EPOR, EPO,
Protein Size: 508 - 分子量
- 53 kDa
- 基因ID
- 2057
- NCBI登录号
- NM_000121, NP_000112
- UniProt
- P19235
- 途径
- JAK/STAT Signaling
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