CBP 抗体 (N-Term)
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- 抗原 See all CBP (CREBBP) 抗体
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- TPAASQALNP QAQKQVGLAT SSPATSQTGP GICMNANFNQ THPGLLNSNS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CREBBP. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CREBBP
- Top Product
- Discover our top product CREBBP Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 2404 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
- 别名
- CREBBP (CREBBP 产品)
- 别名
- CBP antibody, KAT3A antibody, RSTS antibody, AW558298 antibody, CBP/p300 antibody, p300/CBP antibody, RTS antibody, cbp antibody, crebbp antibody, kat3a antibody, rsts antibody, hmm291030 antibody, Nejire antibody, CREB binding protein antibody, CREB binding protein L homeolog antibody, histone acetyltransferase p300 antibody, CREBBP antibody, Crebbp antibody, crebbp.L antibody, LOC100123220 antibody
- 背景
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CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.
Alias Symbols: CBP, KAT3A, RSTS, RTS
Protein Interaction Partner: SUMO1, UBE2I, UBE2D1, TDG, RELA, CREBBP, KLF2, KLF4, WRN, PSME3, COPS2, UBC, BMI1, EID1, ATF4, DYRK1B, DYRK1A, ATF2, CREB1, CDK2, JUN, PPARG, IRF3, HNF4A, KLF1, vIRF-3, AR, vIRF-1, CNTN2, SMAD3, SMAD2, LDLR, STAT1, K8, MTDH, MEIS1, TLR2, EPAS1, MYBL1, LIG
Protein Size: 2404 - 分子量
- 261 kDa
- 基因ID
- 1387
- NCBI登录号
- NM_001079846, NP_001073315
- UniProt
- Q4LE28
- 途径
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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