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ECH1 抗体 (N-Term)

ECH1 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2781318
发货至: 中国
  • 抗原 See all ECH1 抗体
    ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
    抗原表位
    • 16
    • 8
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    N-Term
    适用
    • 30
    • 19
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 犬
    宿主
    • 42
    • 3
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ECH1 antibody is un-conjugated
    应用范围
    • 39
    • 23
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    Western Blotting (WB)
    序列
    PDHSYESLRV TSAQKHVLHV QLNRPNKRNA MNKVFWREMV ECFNKISRDA
    预测反应
    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against ECH1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ECH1
    Top Product
    Discover our top product ECH1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 328 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Xie, Zhang, Lei, Ouyang, Du: "Ananas comosus L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 903258, (2014) (PubMed).

    Xie, Wang, Zhang, Li, Can, Qing, Kung, Zhang: "Enhanced peroxisomal ?-oxidation metabolism in visceral adipose tissues of high-fat diet-fed obesity-resistant C57BL/6 mice." in: Experimental and therapeutic medicine, Vol. 2, Issue 2, pp. 309-315, (2012) (PubMed).

  • 抗原
    ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
    别名
    ECH1 (ECH1 产品)
    别名
    HPXEL antibody, Pxel antibody, AA617331 antibody, enoyl-CoA hydratase 1, peroxisomal antibody, enoyl CoA hydratase 1, peroxisomal antibody, enoyl-CoA hydratase 1 antibody, delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial antibody, enoyl-CoA hydratase 1, peroxisomal L homeolog antibody, enoyl coenzyme A hydratase 1, peroxisomal antibody, ech1 antibody, ECH1 antibody, LOC747511 antibody, ech1.L antibody, Ech1 antibody
    背景
    ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The protein contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
    Alias Symbols: HPXEL
    Protein Interaction Partner: FAM9B, HUWE1, TRAF1, UBC, MDM2, PPP6R3, IQCB1, STAT3, PEX5, EEF1D, DNAJB11, HNRNPUL1, OPA1, APP, HTT, EEF1G, HDAC5, ICT1, TLR10, PAFAH1B3, SERPINB9, CSTF2, TIMP1,
    Protein Size: 328
    分子量
    36 kDa
    基因ID
    1891
    NCBI登录号
    NM_001398, NP_001389
    UniProt
    Q13011
    途径
    Monocarboxylic Acid Catabolic Process
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