REXO4 抗体 (N-Term)
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- 抗原 See all REXO4 抗体
- REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))
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抗原表位
- N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This REXO4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MGKAKVPASK RAPSSPVAKP GPVKTLTRKK NKKKKRFWKS KAREVSKKPA
- 预测反应
- Human: 100%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against REXO4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human REXO4
- Top Product
- Discover our top product REXO4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 422 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))
- 别名
- REXO4 (REXO4 产品)
- 别名
- REXO4 antibody, REX4 antibody, XPMC2 antibody, XPMC2H antibody, Gm111 antibody, Xpmc2h antibody, xpmc2 antibody, im:7156740 antibody, si:ch73-209e20.4 antibody, REX4 homolog, 3'-5' exonuclease antibody, REX4, 3'-5' exonuclease antibody, RNA exonuclease 4 antibody, putative 3'-5' exonuclease antibody, REXO4 antibody, Rexo4 antibody, LOC100229203 antibody, rexo4.S antibody, CAALFM_C112440WA antibody, rexo4 antibody
- 背景
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The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
Alias Symbols: REX4, XPMC2, XPMC2H
Protein Interaction Partner: UBC, SIRT7, ESR2, ESR1,
Protein Size: 422 - 分子量
- 47 kDa
- 基因ID
- 57109
- NCBI登录号
- NM_020385, NP_065118
- UniProt
- Q9GZR2
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