BCL11A 抗体 (N-Term)
(1 reference)-
- 抗原 See all BCL11A 抗体
- BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCL11A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MSRRKQGKPQ HLSKREFSPE PLEAILTDDE PDHGPLGAPE GDHDLLTCGQ
- 预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against BCL11A. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human BCL11A
- Top Product
- Discover our top product BCL11A Primary Antibody
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anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-88) antibody
BCL11A 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (N-Term) antibodyBCL11A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼, 小鸡, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-230) antibodyBCL11A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-243) antibodyBCL11A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-89) antibodyBCL11A 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-210) antibodyBCL11A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-88) antibodyBCL11A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-243) antibodyBCL11A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 637-835) antibodyBCL11A 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal BCL11A-123 unconjugated
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (C-Term) antibodyBCL11A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, Pig, 斑马鱼, 小鸡, 非洲爪蟾, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 835 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 5, pp. 1620-5, (2008) (PubMed).
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: "Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 5, pp. 1620-5, (2008) (PubMed).
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- 抗原
- BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
- 别名
- BCL11A (BCL11A 产品)
- 别名
- 2810047E18Rik antibody, BCL-11A antibody, Ctip1 antibody, D930021L15Rik antibody, Evi9 antibody, Evi9a antibody, Evi9b antibody, Evi9c antibody, mKIAA1809 antibody, BCL11A-L antibody, BCL11A-S antibody, BCL11A-XL antibody, BCL11a-M antibody, CTIP1 antibody, EVI9 antibody, HBFQTL5 antibody, ZNF856 antibody, bcl11a antibody, wu:fi09f10 antibody, zgc:136898 antibody, B cell CLL/lymphoma 11A (zinc finger protein) antibody, B-cell CLL/lymphoma 11A antibody, B-cell CLL/lymphoma 11A L homeolog antibody, B-cell CLL/lymphoma 11Aa antibody, Bcl11a antibody, BCL11A antibody, bcl11a.L antibody, bcl11aa antibody
- 背景
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BCL11A Is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
Alias Symbols: BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856
Protein Interaction Partner: GMCL1P1, ZBTB24, NCK2, LMO1, NR2E3, NR2E1, NR2F2, NR2F1, NR2F6, HDAC2, HDAC1, CDCA3, YME1L1, CDK6, CDK4, ACTC1, APP, UBC, BCL6, BCL11A, Sumo1, SUMO2, SUMO3, SIRT1, MBD3, MTA2, MTA1, CHD4,
Protein Size: 835 - 分子量
- 91 kDa
- 基因ID
- 53335
- NCBI登录号
- NM_022893, NP_075044
- UniProt
- Q9H165
- 途径
- Regulation of Cell Size
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