The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alias Symbols: - Protein Interaction Partner: CUL3, TP53, ZNF512B, CDK2, SMAD2, KPNA2, RFWD2, COPS4, COPS3, TOP1, COPS5, COPS6, UBC, DPPA4, UBXN1, CCDC90B, RBM48, BRD7, IGSF21, UBR1, TRIM5, SETDB1, C14orf1, UNC119, CRMP1, GDF9, SMAD1, GBP2, TLE1, TGFBR1, PTN, GAPDH, EEF1A1, Protein Size: 204