NUP98 抗体 (N-Term)
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- 抗原 See all NUP98 抗体
- NUP98 (Nucleoporin 98kDa (NUP98))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, Saccharomyces cerevisiae, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NUP98 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- AFGTSAFGSS NNTGGLFGNS QTKPGGLFGT SSFSQPATST STGFGFGTST
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against NUP98. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NUP98
- Top Product
- Discover our top product NUP98 Primary Antibody
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anti-Nucleoporin 98kDa (NUP98) (GLFG Motif), (N-Term) antibody
NUP98 适用: 人, 小鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF 宿主: 小鼠 Monoclonal 21A10 unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 1-466) antibodyNUP98 适用: 人, 小鼠, 大鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe WB, ELISA, IF, ICC, DB 宿主: 大鼠 Monoclonal 2H10 unconjugated
anti-Nucleoporin 98kDa (NUP98) (FGxxN Motif), (N-Term) antibodyNUP98 适用: 人, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF 宿主: 小鼠 Monoclonal 13C2 unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 965-1110) antibodyNUP98 适用: 人 WB, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Monoclonal 2H4 unconjugated Recombinant Antibody
anti-Nucleoporin 98kDa (NUP98) (AA 621-920) antibodyNUP98 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 1-606) antibodyNUP98 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 1-110) antibodyNUP98 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1800 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NUP98 (Nucleoporin 98kDa (NUP98))
- 别名
- NUP98 (NUP98 产品)
- 背景
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The nuclear pore complex (NPC) is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kD precursor protein. This cleavage results in the 98 kD nucleoporin as well as a 96 kD nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
Alias Symbols: ADIR2, NUP196, NUP96
Protein Interaction Partner: UBC, SUMO2, SUMO3, CDC37, EED, CDC73, PAF1, ARFGEF2, FBXO6, NXF1, HDAC11, HDAC8, LMNA, HNRNPUL1, CSNK2A1, ECT2, NUP107, RAE1, SUMO1, NUMA1, rev, SIRT7, RAPGEF3, CTNNB1, NUP88, NUP159, NUP82, Nup98, Nup214, Nup188, tat, HDAC1, CREBBP, PTTG1, APC, NPM1, USP
Protein Size: 1800 - 分子量
- 196 kDa
- 基因ID
- 4928
- NCBI登录号
- NM_016320, NP_057404
- 途径
- Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
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