ADNP 抗体 (N-Term)
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- 抗原 See all ADNP 抗体
- ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADNP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EDFKQFEPND FYLKNTTWED VGLWDPSLTK NQDYRTKPFC CSACPFSSKF
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against ADNP. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ADNP
- Top Product
- Discover our top product ADNP Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1102 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
- 别名
- ADNP (ADNP 产品)
- 背景
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Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. ADNP is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. It contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It is also upregulated in normal proliferative tissues. Finally, ADNP may increase the viability of certain cell types through modulation of p53 activity.Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: ADNP1, KIAA0784
Protein Interaction Partner: UBC, SUMO2, EED, RNF2, BMI1, HDAC1, HDAC11, MYC, CDC27, CBX5, PHGDH, RRS1, EBNA1BP2, SAP18, NFIA, SEPT2, EMD, SIRT7, CBX3, CBX1, MAP1LC3B, ARID1A, SMARCC2, SMARCA4,
Protein Size: 1102 - 分子量
- 124 kDa
- 基因ID
- 23394
- NCBI登录号
- NM_015339, NP_056154
- UniProt
- Q9H2P0
- 途径
- Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process
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