NR2E3 抗体 (N-Term)
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- 抗原 See all NR2E3 抗体
- NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR2E3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- METRPTALMS STVAAAAPAA GAASRKESPG RWGLGEDPTG VSPSLQCRVC
- 预测反应
- Cow: 86%, Human: 100%, Mouse: 93%, Pig: 79%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against NR2E3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR2E3
- Top Product
- Discover our top product NR2E3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 410 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity." in: Ophthalmology, Vol. 112, Issue 12, pp. 2115, (2005) (PubMed).
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Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity." in: Ophthalmology, Vol. 112, Issue 12, pp. 2115, (2005) (PubMed).
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- 抗原
- NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))
- 别名
- NR2E3 (NR2E3 产品)
- 别名
- ESCS antibody, PNR antibody, RNR antibody, RP37 antibody, rd7 antibody, LOC100228348 antibody, A930035N01Rik antibody, wu:fj55b07 antibody, zgc:103631 antibody, nuclear receptor subfamily 2 group E member 3 antibody, nuclear receptor subfamily 2, group E, member 3 antibody, NR2E3 antibody, Nr2e3 antibody, nr2e3 antibody
- 背景
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NR2E3 is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. NR2E3 is a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome.This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: PNR, RNR, rd7, ESCS, RP37
Protein Interaction Partner: BCL11A, SIN3A, DHX30, TBL3, MYBBP1A, NCOR1, HDAC3, RBL1, RBBP7, RBBP4, HDAC1, CDK9, VDR, DEDD2, RBFOX2, IRF9, ZNF232, SNAPC1, PPARG, HOXC13, NR3C1, ELAVL2, POLR3D, RARA, NR1D1, CRX, RXRB, RXRA,
Protein Size: 410 - 分子量
- 45 kDa
- 基因ID
- 10002
- NCBI登录号
- NM_014249, NP_055064
- UniProt
- Q9Y5X4
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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