NFAT1 抗体 (C-Term)
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- 抗原 See all NFAT1 抗体
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NFAT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- PTVIQQQNAT SQRAAKNGPP VSDQKEVLPA GVTIKQEQNL DQTYLDDVNE
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against NFATC2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NFATC2
- Top Product
- Discover our top product NFAT1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 925 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
- 别名
- NFATC2 (NFAT1 产品)
- 别名
- NFATC2 antibody, AI607462 antibody, NF-ATc2 antibody, NFAT1 antibody, NFAT1-D antibody, Nfatp antibody, NFATP antibody, nuclear factor of activated T-cells 2 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 antibody, NFATC2 antibody, nfatc2 antibody, Nfatc2 antibody
- 背景
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This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: NFAT1, NFATP
Protein Interaction Partner: GNB2, USP22, UBC, TNPO1, CSE1L, LRRK2, IQGAP1, PPP2R1A, JUN, NFATC2, CREBBP, IRF2BP2, TFAP4, HNRNPA1, TAF9, TUBA1A, KPNB1, SUV39H1, MAPK9, MAPK8, MED31, NFATC2IP, EP300, IRF4, PPP3R1, YWHAZ, PIN1, MEF2D, FOXP3, VIM, PRKCZ, YWHAQ, EGR4, EGR1, PPP3CB,
Protein Size: 925 - 分子量
- 100 kDa
- 基因ID
- 4773
- NCBI登录号
- NM_173091, NP_775114
- UniProt
- Q13469
- 途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling
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