HBP1 抗体 (Middle Region)
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- 抗原 See all HBP1 抗体
- HBP1 (HMG Box-Containing Protein 1 (HBP1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HBP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SVILGDRWKK MKNEERRMYT LEAKALAEEQ KRLNPDCWKR KRTNSGSQQH
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against HBP1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HBP1
- Top Product
- Discover our top product HBP1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 514 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression." in: Nucleic acids research, Vol. 40, Issue 3, pp. 981-95, (2012) (PubMed).
: "miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1." in: Breast cancer research and treatment, Vol. 126, Issue 3, pp. 565-75, (2011) (PubMed).
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The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression." in: Nucleic acids research, Vol. 40, Issue 3, pp. 981-95, (2012) (PubMed).
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- 抗原
- HBP1 (HMG Box-Containing Protein 1 (HBP1))
- 别名
- HBP1 (HBP1 产品)
- 别名
- 1700058O05Rik antibody, BE629963 antibody, C330012F01Rik antibody, C86454 antibody, hbp1-B antibody, Hmgb1 antibody, wu:fj62c10 antibody, zgc:112297 antibody, high mobility group box transcription factor 1 antibody, HMG-box transcription factor 1 antibody, HMG-box transcription factor 1 L homeolog antibody, Hbp1 antibody, HBP1 antibody, hbp1.L antibody, hbp1 antibody
- 背景
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HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4.
Alias Symbols: FLJ16340
Protein Interaction Partner: FBXW11, UBC, TMEM37, SMAD1, ZNF212, KIAA1279, EWSR1, CD2AP, EP300, CREBBP, MYC, ANKRD2, SIN3A, SAP30, TCF4, HDAC1, RBL2, RB1,
Protein Size: 514 - 分子量
- 58 kDa
- 基因ID
- 26959
- NCBI登录号
- NM_012257, NP_036389
- UniProt
- O60381
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