NCOA2 抗体 (N-Term)
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- 抗原 See all NCOA2 抗体
- NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCOA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MSGMGENTSD PSRAETRKRK ECPDQLGPSP KRNTEKRNRE QENKYIEELA
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against NCOA2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NCOA2
- Top Product
- Discover our top product NCOA2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1464 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 4, pp. 977-83, (2008) (PubMed).
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ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 4, pp. 977-83, (2008) (PubMed).
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- 抗原
- NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))
- 别名
- NCOA2 (NCOA2 产品)
- 背景
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NCOA2 is the transcriptional coactivator for steroid receptors and nuclear receptors. NCOA2 is the coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). NCOA2 is required with NCOA1 to control energy balance
Alias Symbols: GRIP1, KAT13C, MGC138808, NCoA-2, TIF2, SRC2, bHLHe75
Protein Interaction Partner: VDR, PSMB9, PPARG, ESR1, PML, UBC, TP53, TAF9, Pias3, tat, THRB, NR3C1, EP300, NR1I2, RXRA, RARA, CREBBP, AHR, KANK2, MAGEA11, NCOA1, HHV8GK18_gp81, ESR2, PGR, SUMO2, CAD, ATR, HSPA2, CC2D1A, UBR5, TBK1, WDHD1, USO1, STAT6, NCOA3, THRA, CDK4, CCND3, EID1,
Protein Size: 1464 - 分子量
- 159 kDa
- 基因ID
- 10499
- NCBI登录号
- NM_006540, NP_006531
- UniProt
- Q15596
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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