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- 抗原 See all CREB3 抗体
- CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
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抗原表位
- Middle Region
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适用
- 人, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CREB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PPLEWPFPDL FSEPLCRGPI LPLQANLTRK GGWLPTGSPS VILQDRYSG
- 预测反应
- Cow: 80%, Dog: 80%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CREB3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CREB3
- Top Product
- Discover our top product CREB3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 371 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Lithium response and genetic variation in the CREB family of genes." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 500-4, (2008) (PubMed).
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Lithium response and genetic variation in the CREB family of genes." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 500-4, (2008) (PubMed).
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- 抗原
- CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
- 别名
- CREB3 (CREB3 产品)
- 别名
- LUMAN antibody, LZIP antibody, AU044960 antibody, AW538053 antibody, C80076 antibody, LZIP-1 antibody, LZIP-2 antibody, Luman antibody, creb3 antibody, luman antibody, lzip antibody, cAMP responsive element binding protein 3 antibody, cAMP responsive element binding protein 3 S homeolog antibody, CREB3 antibody, Creb3 antibody, creb3.S antibody
- 背景
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CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LUMAN, LZIP, MGC15333, MGC19782
Protein Interaction Partner: COPS5, HCFC1, JUN, CREB3L1, CREB3L3, CREB3, NFE2L3, NFE2L2, DDIT3, CEBPG, ATF4, ATF3, TTLL5, RRAS2, OS9, RABAC1, SQLE, BCAT2, CLP1, UBC, HDAC3, MALL, NFIL3, APPBP2, STX8, BNIP2, CCR1, EMD,
Protein Size: 371 - 分子量
- 41 kDa
- 基因ID
- 10488
- NCBI登录号
- NM_006368, NP_006359
- UniProt
- O43889
- 途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response
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