TSG101 抗体 (C-Term)
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- 抗原 See all TSG101 抗体
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 兔, 山羊, 马, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSG101 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TIFYLGEALR RGVIDLDVFL KHVRLLSRKQ FQLRALMQKA RKTAGLSDLY
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TSG101. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TSG101
- Top Product
- Discover our top product TSG101 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 390 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Enhanced alpha1 microglobulin secretion from Hepatitis E virus ORF3-expressing human hepatoma cells is mediated by the tumor susceptibility gene 101." in: The Journal of biological chemistry, Vol. 281, Issue 12, pp. 8135-42, (2006) (PubMed).
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Enhanced alpha1 microglobulin secretion from Hepatitis E virus ORF3-expressing human hepatoma cells is mediated by the tumor susceptibility gene 101." in: The Journal of biological chemistry, Vol. 281, Issue 12, pp. 8135-42, (2006) (PubMed).
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- 抗原
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
- 别名
- TSG101 (TSG101 产品)
- 别名
- CG9712 antibody, DmTSG101 antibody, Dmel\\CG9712 antibody, ESCRT-I antibody, Tsg101 antibody, burs antibody, dTSg101 antibody, dTsg101 antibody, dVps23 antibody, ept antibody, tsg101 antibody, vps23 antibody, TSG101 antibody, MGC76193 antibody, TSG10 antibody, VPS23 antibody, AI255943 antibody, CC2 antibody, Rw antibody, zgc:86926 antibody, tumor susceptibility 101 antibody, Tumor susceptibility gene 101 antibody, Tumor Susceptibility Gene homolog antibody, tumor susceptibility gene 101 antibody, tumor susceptibility 101a antibody, tumor susceptibility 101 L homeolog antibody, TSG101 antibody, tsg-101 antibody, tsg101 antibody, Tsg101 antibody, tsg101a antibody, tsg101.L antibody
- 背景
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TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. TSG101 contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. TSG101 may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of TSG101 appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in TSG101 gene occur in high frequency in breast cancer. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Alias Symbols: TSG10, VPS23
Protein Interaction Partner: USHBP1, CEP55, VPS37C, VPS28, AATF, MGRN1, PDLIM7, TAX1BP1, KRT31, KRT13, KIFC3, DAPK3, AR, FAM9B, VPS37A, HAUS1, SYCE1, UBC, LRSAM1, ADRB2, MVB12A, UBAP1, CDKN1A, HGS, gag, gag-pol, GRB2, CDS2, ZFYVE9, VCP, VPS37B, WDR12, XPO1, UBD, ARRDC1, KCNN4, RAB11F
Protein Size: 390 - 分子量
- 44 kDa
- 基因ID
- 7251
- NCBI登录号
- NM_006292, NP_006283
- UniProt
- Q99816
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