NR4A2 抗体 (N-Term)
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- 抗原 See all NR4A2 抗体
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, 犬, 豚鼠, 马, 兔, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR4A2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MPCVQAQYGS SPQGASPASQ SYSYHSSGEY SSDFLTPEFV KFSMDLTNTE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against NR4A2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR4A2
- Top Product
- Discover our top product NR4A2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 598 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Epigenetic reprogramming of cortical neurons through alteration of dopaminergic circuits." in: Molecular psychiatry, Vol. 19, Issue 11, pp. 1193-200, (2014) (PubMed).
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Epigenetic reprogramming of cortical neurons through alteration of dopaminergic circuits." in: Molecular psychiatry, Vol. 19, Issue 11, pp. 1193-200, (2014) (PubMed).
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- 抗原
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
- 别名
- NR4A2 (NR4A2 产品)
- 别名
- nr41/42/43 antibody, Nr4a2 antibody, nurr1 antibody, not antibody, rnr1 antibody, hzf-3 antibody, tinur antibody, NGFI-B antibody, HZF-3 antibody, NOT antibody, NURR1 antibody, RNR1 antibody, TINUR antibody, Nurr1 antibody, RNR-1 antibody, TINOR antibody, ngf1b antibody, nr4a2 antibody, zgc:92696 antibody, nuclear receptor subfamily 4 group A member 2 antibody, nuclear receptor antibody, nuclear receptor subfamily 4, group A, member 2 antibody, nuclear receptor subfamily 4, group A, member 2b antibody, NR4A2 antibody, nr41/42/43 antibody, nr4a2 antibody, Nr4a2 antibody, nr4a2b antibody
- 背景
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NR4A2 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The protein may act as a transcription factor. Mutations in NR4A2 gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of NR4A2 gene may be associated with rheumatoid arthritis.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HZF-3, NOT, NURR1, RNR1, TINUR
Protein Interaction Partner: CDKN2D, TCEAL5, BAZ1B, ELAVL1, COPS5, RXRB, RXRA, RUNX1, SMARCA4, SMARCA2, SIN3A, NCOR2, SFPQ, PIAS4, RPS6KA1, CDKN1C, RARB, RARA, CREB1,
Protein Size: 598 - 分子量
- 66 kDa
- 基因ID
- 4929
- NCBI登录号
- NM_006186, NP_006177
- UniProt
- P43354
- 途径
- Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway
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