RBM5 抗体 (N-Term)
-
- 抗原 See all RBM5 抗体
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Saccharomyces cerevisiae
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RBM5 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- GSDKRVSRTE RSGRYGSIID RDDRDERESR SRRRDSDYKR SSDDRRGDRY
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%
- 产品特性
- This is a rabbit polyclonal antibody against RBM5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RBM5
- Top Product
- Discover our top product RBM5 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 815 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
- 别名
- RBM5 (RBM5 产品)
- 别名
- wu:fc25a08 antibody, wu:fe06f12 antibody, g15 antibody, h37 antibody, luca15 antibody, rbm5 antibody, rmb5 antibody, RBM5 antibody, G15 antibody, LUCA15 antibody, RMB5 antibody, D030069N10Rik antibody, RNA binding motif protein 5 antibody, RNA binding motif protein 5 S homeolog antibody, RNA binding motif protein 5 L homeolog antibody, rbm5 antibody, rbm5.S antibody, RBM5 antibody, rbm5.L antibody, Rbm5 antibody
- 背景
-
RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Alias Symbols: FLJ39876, G15, H37, LUCA15, RMB5
Protein Interaction Partner: UBC, RNF2, SUZ12, WDR77, WBP11, LSM8, PRPF19, U2SURP, SNRNP200, U2AF2, PRPF8, ILF3, DHX15, LIG4, COPS5, SF3A2, SUMO2, GAPDH, BCL2L1, LRIF1,
Protein Size: 815 - 分子量
- 92 kDa
- 基因ID
- 10181
- NCBI登录号
- NM_005778, NP_005769
- UniProt
- P52756
- 途径
- Ribonucleoprotein Complex Subunit Organization
-