NR1H3 抗体 (N-Term)
-
- 抗原 See all NR1H3 抗体
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
-
抗原表位
- N-Term
-
适用
- 人, Cow, 山羊, 犬, 马, 兔, Pig
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This NR1H3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- MSLWLGAPVP DIPPDSAVEL WKPGAQDASS QAQGGSSCIL REEARMPHSA
- 预测反应
- Cow: 85%, Dog: 79%, Goat: 85%, Horse: 79%, Human: 100%, Pig: 77%, Rabbit: 86%
- 产品特性
- This is a rabbit polyclonal antibody against NR1H3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR1H3
- Top Product
- Discover our top product NR1H3 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 447 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- 别名
- NR1H3 (NR1H3 产品)
- 别名
- NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
- 背景
-
Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
Alias Symbols: LXRA, LXR-a, RLD-1
Protein Interaction Partner: RXRG, RXRB, MDFI, SUV39H1, KDM1A, BARD1, MSTO1, HSP90AA1, PIAS1, APP, NR3C1, MYC, ZXDC, TMEM161A, ING3, NCOA6, NCOR1, KAT2B, EIF3I, NRIP1, NCOA3, SRC, RXRA, FOXO3, ACTN1, SS18L1, LZTR1, EDF1, RARA, NR0B2, SYT1, PPARA, SIRT1, UBC, CEP350,
Protein Size: 447 - 分子量
- 50 kDa
- 基因ID
- 10062
- NCBI登录号
- NM_005693, NP_005684
- UniProt
- Q13133
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
-