MAF 抗体 (N-Term)
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- 抗原 See all MAF 抗体
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 马, 豚鼠, Pig, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAF antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MASELAMSNS DLPTSPLAME YVNDFDLMKF EVKKEPVETD RIISQCGRLI
- 预测反应
- Cow: 100%, Dog: 82%, Guinea Pig: 79%, Horse: 82%, Human: 100%, Mouse: 100%, Pig: 82%, Rabbit: 82%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against MAF. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAF
- Top Product
- Discover our top product MAF Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 373 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
- 别名
- MAF (MAF 产品)
- 别名
- MAF antibody, DKFZp459D1731 antibody, 2810401A20Rik antibody, A230108G15Rik antibody, AW047063 antibody, c-maf antibody, CCA4 antibody, c-MAF antibody, Maf2 antibody, cMaf antibody, Z-cmaf antibody, c-Maf antibody, fl13d12 antibody, wu:fl13d12 antibody, C-Maf antibody, MAF bZIP transcription factor antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) antibody, avian musculoaponeurotic fibrosarcoma oncogene homolog antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a) antibody, MAF antibody, Maf antibody, mafa antibody
- 背景
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MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: MGC71685, c-MAF
Protein Interaction Partner: MAFB, FOSL1, MAF, FOS, ATF4, AHR, SUMO1, UBE2I, PML, SIN3A, HDAC2, SMARCA5, CEBPA, KDM5B, MAFA, SOX9, EP300, MAFG, USF2, CREBBP, MYB, JUN, ETS1, HOXD12,
Protein Size: 373 - 分子量
- 38 kDa
- 基因ID
- 4094
- NCBI登录号
- NM_001031804, NP_001026974
- UniProt
- O75444
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