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ETS2 抗体 (Middle Region)

ETS2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, 绵羊, 山羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780665
发货至: 中国
  • 抗原 See all ETS2 抗体
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    抗原表位
    • 9
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 46
    • 9
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, 绵羊, 山羊, 斑马鱼
    宿主
    • 41
    • 6
    克隆类型
    • 44
    • 3
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ETS2 antibody is un-conjugated
    应用范围
    • 35
    • 22
    • 16
    • 15
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DPDEVARRWG KRKNKPKMNY EKLSRGLRYY YDKNIIHKTS GKRYVYRFVC
    预测反应
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against ETS2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human ETS2
    Top Product
    Discover our top product ETS2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 469 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    别名
    ETS2 (ETS2 产品)
    别名
    0123/09 antibody, 0608/07 antibody, 0998/12 antibody, 3520 antibody, CG17077 antibody, CG8705 antibody, D-Ets-2 antibody, D-ets-2 antibody, DMPOINT1A antibody, Dmel\\CG17077 antibody, E(E2F)3D antibody, EK3-2 antibody, ETS2 antibody, EY3-1 antibody, Ets antibody, Ets2 antibody, Ets58AB antibody, Ets94F antibody, PNT-P1 antibody, PNTP1 antibody, PNTP2 antibody, POINT antibody, Pnt antibody, Pnt-P1 antibody, PntP1 antibody, PntP2 antibody, Pointed-P1 antibody, ets94F antibody, l(3)07825 antibody, l(3)j1B7 antibody, l(3)s118306 antibody, png antibody, pnt-P1 antibody, pnt-P2 antibody, pntP2 antibody, pntegfr antibody, pointed-RC antibody, ptd antibody, zgc:92106 antibody, wu:fe02h08 antibody, wu:fk74c05 antibody, AU022856 antibody, Ets-2 antibody, ETS2IT1 antibody, c-ets-2 antibody, pointed antibody, v-ets avian erythroblastosis virus E26 oncogene homolog 2 antibody, E26 avian leukemia oncogene 2, 3' domain antibody, ETS proto-oncogene 2, transcription factor antibody, pnt antibody, ets2 antibody, Ets2 antibody, ETS2 antibody
    背景
    ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ETS2IT1
    Protein Interaction Partner: UBC, RFWD2, TWIST1, POU5F1, TWIST2, ZFYVE9, SRA1, XPO1, TP53, SUMO2, EP300, CREBBP, NCOR1, NCOA3, SRC, ZMYND11, TDP2, STAT5B, CDK10, SMARCA4, JUN, ERG, ETS2, ETS1, NR3C1, GATA3, FOS, SPI1, BRCA1,
    Protein Size: 469
    分子量
    53 kDa
    基因ID
    2114
    NCBI登录号
    NM_005239, NP_005230
    UniProt
    P15036
    途径
    EGFR Signaling Pathway, Myometrial Relaxation and Contraction
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