NRF1 抗体 (N-Term)
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- 抗原 See all NRF1 抗体
- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NRF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MEEHGVTQTE HMATIEAHAV AQQVQQVHVA TYTEHSMLSA DEDSPSSPED
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against NRF1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NRF1
- Top Product
- Discover our top product NRF1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 503 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
- 别名
- NRF1 (NRF1 产品)
- 别名
- ALPHA-PAL antibody, C87038 antibody, D6Ertd415e antibody, SC:BZ3C13.1 antibody, SC:bZ3C13.2 antibody, ube2h antibody, Nfe2l1_retired antibody, IBR/F antibody, NRF1 antibody, alpha-pal antibody, nrf-1 antibody, LOC100220087 antibody, nuclear respiratory factor 1 antibody, nuclear respiratory factor 1 S homeolog antibody, NRF1 antibody, Nrf1 antibody, nrf1 antibody, nrf1.S antibody
- 背景
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NRF1 is a phosphorylated nuclear protein with a bZIP domain. This protein homodimerizes and functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
Alias Symbols: ALPHA-PAL
Protein Interaction Partner: POGZ, TRAF2, SP4, FHL2, DYNLL1, CSNK2B, CSNK2A1, UBC, HHV8GK18_gp81, CEBPB, PARP1, PPRC1, MAFF, PPARGC1A, Dynlt1b, CDK1, MRPL57, TFAM,
Protein Size: 503 - 分子量
- 53 kDa
- 基因ID
- 4899
- NCBI登录号
- NM_005011, NP_005002
- UniProt
- Q16656
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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