ONECUT1 抗体 (Middle Region)
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- 抗原 See all ONECUT1 抗体
- ONECUT1 (One Cut Homeobox 1 (ONECUT1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ONECUT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ITISQQLGLE LSTVSNFFMN ARRRSLDKWQ DEGSSNSGNS SSSSSTCTKA
- 预测反应
- Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against ONECUT1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ONECUT1
- Top Product
- Discover our top product ONECUT1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 465 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Hepatocyte nuclear factor 6 suppresses the migration and invasive growth of lung cancer cells through p53 and the inhibition of epithelial-mesenchymal transition." in: The Journal of biological chemistry, Vol. 288, Issue 43, pp. 31206-16, (2013) (PubMed).
: "Distribution of the interstitial Cajal-like cells in the gallbladder and extrahepatic biliary duct of the guinea-pig." in: Acta histochemica, Vol. 111, Issue 2, pp. 157-65, (2009) (PubMed).
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Hepatocyte nuclear factor 6 suppresses the migration and invasive growth of lung cancer cells through p53 and the inhibition of epithelial-mesenchymal transition." in: The Journal of biological chemistry, Vol. 288, Issue 43, pp. 31206-16, (2013) (PubMed).
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- 抗原
- ONECUT1 (One Cut Homeobox 1 (ONECUT1))
- 别名
- ONECUT1 (ONECUT1 产品)
- 别名
- D9Ertd423e antibody, HNF-6 antibody, Hfh12 antibody, Hnf6 antibody, Hnf6b antibody, OC-1 antibody, Oc1 antibody, onecut antibody, onecut1 antibody, id:ibd5005 antibody, HNF6 antibody, HNF6A antibody, HNF-6a antibody, oc1 antibody, onecut1l antibody, zgc:65904 antibody, zgc:77450 antibody, one cut domain, family member 1 antibody, one cut homeobox 1 antibody, one cut domain, family member, like antibody, Onecut1 antibody, onecutl antibody, ONECUT1 antibody, onecut1 antibody
- 背景
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ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Alias Symbols: HNF-6, HNF6, HNF6A
Protein Interaction Partner: NR0B2, KAT2B, FOXA2, CREBBP, NR3C1, FOXA1,
Protein Size: 465 - 分子量
- 51 kDa
- 基因ID
- 3175
- NCBI登录号
- NM_004498, NP_004489
- UniProt
- Q9UBC0
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