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RNF14 抗体 (C-Term)

RNF14 适用: 人, 大鼠, Cow, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780586
发货至: 中国
  • 抗原 See all RNF14 抗体
    RNF14 (Ring Finger Protein 14 (RNF14))
    抗原表位
    • 10
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 52
    • 27
    • 24
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, Cow, 犬, 兔
    宿主
    • 50
    • 2
    克隆类型
    • 50
    • 2
    多克隆
    标记
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF14 antibody is un-conjugated
    应用范围
    • 46
    • 18
    • 13
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    CMQYFCWICM GSLSRANPYK HFNDPGSPCF NRLFYAVDVD DDIWEDEVED
    预测反应
    Cow: 79%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against RNF14. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human RNF14
    Top Product
    Discover our top product RNF14 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 474 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lin, Wu, Tarr, Lindenberg, St-Pierre, Zhang, Mootha, Jäger, Vianna, Reznick, Cui, Manieri, Donovan, Wu, Cooper, Fan, Rohas, Zavacki, Cinti, Shulman, Lowell, Krainc, Spiegelman: "Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice." in: Cell, Vol. 119, Issue 1, pp. 121-35, (2004) (PubMed).

  • 抗原
    RNF14 (Ring Finger Protein 14 (RNF14))
    别名
    RNF14 (RNF14 产品)
    别名
    ARA54 antibody, HFB30 antibody, TRIAD2 antibody, 2310075C09Rik antibody, 2610005D23Rik antibody, AA986456 antibody, AU041447 antibody, D18Ertd188e antibody, D7Bwg0165e antibody, Triad2 antibody, ring finger protein 14 antibody, RNF14 antibody, Rnf14 antibody
    背景
    RNF14 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
    Alias Symbols: ARA54, HFB30, TRIAD2, HRIHFB2038
    Protein Interaction Partner: UBE2E2, UBE2D1, DACH1, UBE2D4, LEF1, TCF3, HNF1A, TCF4, CTNNB1, UBC, AR, FAM46A, TNFAIP3, ECT2, UBE2E3, UBE2E1, PHF7, TAGLN, HNRNPA1, VDR, UBE2D3, UBE2D2, UBE2U, UBE2W, UBE2V1, NCOA4, NR3C1, ESR1, RNF14,
    Protein Size: 474
    分子量
    52 kDa
    基因ID
    9604
    NCBI登录号
    NM_183401, NP_899648
    UniProt
    Q9UBS8
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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