RNF14 抗体 (C-Term)
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- 抗原 See all RNF14 抗体
- RNF14 (Ring Finger Protein 14 (RNF14))
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抗原表位
- C-Term
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适用
- 人, 大鼠, Cow, 犬, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF14 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- CMQYFCWICM GSLSRANPYK HFNDPGSPCF NRLFYAVDVD DDIWEDEVED
- 预测反应
- Cow: 79%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against RNF14. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF14
- Top Product
- Discover our top product RNF14 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 474 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice." in: Cell, Vol. 119, Issue 1, pp. 121-35, (2004) (PubMed).
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Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice." in: Cell, Vol. 119, Issue 1, pp. 121-35, (2004) (PubMed).
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- 抗原
- RNF14 (Ring Finger Protein 14 (RNF14))
- 别名
- RNF14 (RNF14 产品)
- 别名
- ARA54 antibody, HFB30 antibody, TRIAD2 antibody, 2310075C09Rik antibody, 2610005D23Rik antibody, AA986456 antibody, AU041447 antibody, D18Ertd188e antibody, D7Bwg0165e antibody, Triad2 antibody, ring finger protein 14 antibody, RNF14 antibody, Rnf14 antibody
- 背景
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RNF14 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Alias Symbols: ARA54, HFB30, TRIAD2, HRIHFB2038
Protein Interaction Partner: UBE2E2, UBE2D1, DACH1, UBE2D4, LEF1, TCF3, HNF1A, TCF4, CTNNB1, UBC, AR, FAM46A, TNFAIP3, ECT2, UBE2E3, UBE2E1, PHF7, TAGLN, HNRNPA1, VDR, UBE2D3, UBE2D2, UBE2U, UBE2W, UBE2V1, NCOA4, NR3C1, ESR1, RNF14,
Protein Size: 474 - 分子量
- 52 kDa
- 基因ID
- 9604
- NCBI登录号
- NM_183401, NP_899648
- UniProt
- Q9UBS8
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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