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RNF14 抗体 (C-Term)

RNF14 适用: 人, 大鼠, Cow, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780586
发货至: 中国
  • 抗原 See all RNF14 抗体
    RNF14 (Ring Finger Protein 14 (RNF14))
    抗原表位
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 48
    • 27
    • 24
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, Cow, 犬, 兔
    宿主
    • 46
    • 2
    克隆类型
    • 45
    • 3
    多克隆
    标记
    • 23
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF14 antibody is un-conjugated
    应用范围
    • 42
    • 13
    • 13
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    CMQYFCWICM GSLSRANPYK HFNDPGSPCF NRLFYAVDVD DDIWEDEVED
    预测反应
    Cow: 79%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against RNF14. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human RNF14
    Top Product
    Discover our top product RNF14 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 474 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lin, Wu, Tarr, Lindenberg, St-Pierre, Zhang, Mootha, Jäger, Vianna, Reznick, Cui, Manieri, Donovan, Wu, Cooper, Fan, Rohas, Zavacki, Cinti, Shulman, Lowell, Krainc, Spiegelman: "Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice." in: Cell, Vol. 119, Issue 1, pp. 121-35, (2004) (PubMed).

  • 抗原
    RNF14 (Ring Finger Protein 14 (RNF14))
    别名
    RNF14 (RNF14 产品)
    背景
    RNF14 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
    Alias Symbols: ARA54, HFB30, TRIAD2, HRIHFB2038
    Protein Interaction Partner: UBE2E2, UBE2D1, DACH1, UBE2D4, LEF1, TCF3, HNF1A, TCF4, CTNNB1, UBC, AR, FAM46A, TNFAIP3, ECT2, UBE2E3, UBE2E1, PHF7, TAGLN, HNRNPA1, VDR, UBE2D3, UBE2D2, UBE2U, UBE2W, UBE2V1, NCOA4, NR3C1, ESR1, RNF14,
    Protein Size: 474
    分子量
    52 kDa
    基因ID
    9604
    NCBI登录号
    NM_183401, NP_899648
    UniProt
    Q9UBS8
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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