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COPS2 抗体 (N-Term)

COPS2 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780578
发货至: 中国
  • 抗原 See all COPS2 抗体
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    抗原表位
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 54
    • 45
    • 41
    • 9
    • 9
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 兔, 豚鼠, 马
    宿主
    • 51
    • 2
    • 1
    克隆类型
    • 52
    • 2
    多克隆
    标记
    • 25
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS2 antibody is un-conjugated
    应用范围
    • 47
    • 19
    • 18
    • 13
    • 11
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MSDMEDDFMC DDEEDYDLEY SEDSNSEPNV DLENQYYNSK ALKEDDPKAA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against COPS2. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human COPS2
    Top Product
    Discover our top product COPS2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 443 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Pick, Golan, Zimbler, Guo, Sharaby, Tsuge, Hofmann, Wei: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).

  • 抗原
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    别名
    COPS2 (COPS2 产品)
    别名
    COPS2 antibody, ALIEN antibody, CSN2 antibody, SGN2 antibody, TRIP15 antibody, wu:fc05f05 antibody, wu:fc06g10 antibody, wu:fc60f04 antibody, wu:fl94f12 antibody, zgc:86624 antibody, csn2 antibody, Tb03.48O8.600 antibody, Trip15 antibody, AI315723 antibody, C85265 antibody, Csn2 antibody, Sgn2 antibody, alien-like antibody, ATCSN2 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 12 antibody, COP12 antibody, FUSCA 12 antibody, T20P8.4 antibody, T20P8_4 antibody, COP9 signalosome subunit 2 antibody, COP9 signalosome subunit 2 L homeolog antibody, COP9 signalosome complex subunit 2 antibody, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) antibody, proteasome family protein antibody, COPS2 antibody, cops2 antibody, cops2.L antibody, Tb927.3.2320 antibody, AOR_1_576084 antibody, PTRG_07106 antibody, LOC100283498 antibody, Cops2 antibody, csn-2 antibody, FUS12 antibody
    背景
    COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
    Alias Symbols: ALIEN, CSN2, SGN2, TRIP15
    Protein Interaction Partner: UBC, GPS1, Map3k10, 5830415F09Rik, Taf1b, EP300, Crebbp, cul1, COPS7B, EPB41L1, COPS5, FBXW4, SENP8, vpr, IRF5, COPS4, COPS7A, COPS6, COPS8, COPS3, PMPCA, SEPHS1, EHBP1L1, SLAIN2, GAPVD1, PFKFB2, SEPT2, IRS2, GRK5, DDB2, LRR1, DCAF11, DDA1, RFWD2, DCAF8,
    Protein Size: 443
    分子量
    51 kDa
    基因ID
    9318
    NCBI登录号
    NM_004236, NP_004227
    UniProt
    P61203
    途径
    Cell Division Cycle
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