TANK 抗体 (N-Term)
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- 抗原 See all TANK 抗体
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 马, 犬, 豚鼠, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TANK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- DKNIGEQLNK AYEAFRQACM DRDSAVKELQ QKTENYEQRI REQQEQLSLQ
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against TANK. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TANK
- Top Product
- Discover our top product TANK Primary Antibody
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anti-TRAF Family Member-Associated NFKB Activator (TANK) (AA 131-369) antibody
TANK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (AA 4-98) antibodyTANK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (Internal Region) antibodyTANK 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-119) antibodyTANK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (AA 88-114) antibodyTANK 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22057 unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (Center) antibodyTANK 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (C-Term) antibodyTANK 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (N-Term) antibodyTANK 适用: 人, 兔, Cow, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (N-Term) antibodyTANK 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (N-Term) antibodyTANK 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 425 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- 别名
- TANK (TANK 产品)
- 别名
- I-TRAF antibody, ITRAF antibody, TRAF2 antibody, C86182 antibody, E430026L09Rik antibody, zgc:153048 antibody, i-traf antibody, tank antibody, traf2 antibody, TRAF family member associated NFKB activator antibody, TRAF family member-associated Nf-kappa B activator antibody, TRAF family member-associated NFKB activator antibody, TRAF family member associated NFKB activator L homeolog antibody, TANK antibody, Tank antibody, tank antibody, tank.L antibody
- 背景
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The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: I-TRAF, TRAF2
Protein Interaction Partner: CEP63, TP53BP2, SRSF11, UBC, TBK1, BIRC3, BIRC2, INPP5K, ATP6V1H, RACGAP1, TANK, IKBKE, IKBKG, AIMP2, TRAF2, TRAF1, SDC4, PLK1, SMAD3, LAMC1, KPNA2, HLA-C, FBLN1, COPB1, BIK, APP, TRAF3, TAB2, MAP3K14, HERC2, CD40, CBLB, TICAM1, APBA3, MARCH5, ZC3H12A, MA
Protein Size: 425 - 分子量
- 48 kDa
- 基因ID
- 10010
- NCBI登录号
- NM_004180, NP_004171
- UniProt
- Q92844
- 途径
- p53 Pathway, TLR signaling, Activation of Innate immune Response
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