TRIM21 抗体 (N-Term)
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- 抗原 See all TRIM21 抗体
- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Pig, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIM21 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- CPVCRQRFLL KNLRPNRQLA NMVNNLKEIS QEAREGTQGE RCAVHGERLH
- 预测反应
- Cow: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against TRIM21. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM21
- Top Product
- Discover our top product TRIM21 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 475 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
- 别名
- TRIM21 (TRIM21 产品)
- 背景
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TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RNF81, RO52, SSA, SSA1
Protein Interaction Partner: TRIM39, IGHV4-31, TXN2, GRAP, UBE2I, TRIM21, IGHG1, USP15, HAUS2, UBE2D2, UBC, FBXO6, UBD, NPM1, PAN2, ROR1, NOS2, MYC, IQCB1, USP2, VCP, USP4, CDC34, CBL, UBC4, UBE2C, UBE2L3, UBE2H, UBE2D1, TROVE2, TRIM27, MNAT1, FCGR2A, CD52, DCP2, ZFPM1, TRIM5, TRIM8,
Protein Size: 475 - 分子量
- 54 kDa
- 基因ID
- 6737
- NCBI登录号
- NM_003141, NP_003132
- UniProt
- P19474
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