SMARCE1 抗体 (N-Term)
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- 抗原 See all SMARCE1 抗体
- SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, 犬, 马, Cow, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMARCE1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MSKRPSYAPP PTPAPATQMP STPGFVGYNP YSHLAYNNYR LGGNPGTNSR
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SMARCE1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCE1
- Top Product
- Discover our top product SMARCE1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 411 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
- 别名
- SMARCE1 (SMARCE1 产品)
- 别名
- BAF57 antibody, XBaf57 antibody, MGC52696 antibody, MGC69429 antibody, MGC81726 antibody, SMARCE1 antibody, DKFZp459O2235 antibody, fb54d11 antibody, wu:fb33d02 antibody, wu:fb54d11 antibody, Baf57 antibody, 2810417B20Rik antibody, 5830412H02Rik antibody, 9030408N19Rik antibody, Baf27 antibody, RGD1304726 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 L homeolog antibody, smarce1 antibody, SMARCE1 antibody, smarce1.L antibody, Smarce1 antibody
- 背景
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SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
Alias Symbols: BAF57
Protein Interaction Partner: NOTCH2NL, KRTAP10-9, CCDC172, NBPF22P, TXLNA, MIPOL1, KRT40, MRFAP1L1, SYCE1, ING5, USHBP1, CEP70, CEP63, CCDC136, RINT1, TRIM54, AMOTL2, MED4, TFIP11, NUP62, MTUS2, EXOC7, RALBP1, SPAG5, JAKMIP2, TRIP10, STX11, CEP170P1, MEOX2, KRT31, KRT15, KIFC3, GOLGA
Protein Size: 411 - 分子量
- 47 kDa
- 基因ID
- 6605
- NCBI登录号
- NM_003079, NP_003070
- UniProt
- Q969G3
- 途径
- Chromatin Binding
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