IGHMBP2 抗体 (N-Term)
(1 reference)-
- 抗原 See all IGHMBP2 抗体
- IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IGHMBP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QLLELERDAE VEERRSWQEH SSLRELQSRG VCLLKLQVSS QRTGLYGQRL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Ighmbp2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product IGHMBP2 Primary Antibody
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anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) (AA 540-720) antibody
IGHMBP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) antibodyIGHMBP2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) (AA 646-884) antibodyIGHMBP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) (N-Term) antibodyIGHMBP2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) (N-Term) antibodyIGHMBP2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 993 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 5, pp. 855-66, (2016) (PubMed).
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: "Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 5, pp. 855-66, (2016) (PubMed).
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- 抗原
- IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))
- 别名
- Ighmbp2 (IGHMBP2 产品)
- 别名
- NV12364 antibody, CATF1 antibody, HCSA antibody, HMN6 antibody, SMARD1 antibody, SMUBP2 antibody, ZFAND7 antibody, AEP antibody, Catf1 antibody, RIPE3b1 antibody, Smbp-2 antibody, Smbp2 antibody, Smubp2 antibody, nmd antibody, sma antibody, RIP-1 antibody, RIP1 antibody, immunoglobulin mu binding protein 2 antibody, IGHMBP2 antibody, Ighmbp2 antibody, ighmbp2 antibody
- 背景
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Ighmbp2 is a 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Ighmbp2 acts as a transcription regulator. Ighmbp2 is required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Ighmbp2 exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Ighmbp2 binds to the insulin II gene RIPE3B enhancer region. Ighmbp2 may be involved in translation.Ighmbp2 is a DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region.Ighmbp2 preferentially binds to the 5'-GGGCT-3' motif. Ighmbp2 interacts with tRNA-Tyr.
Alias Symbols: AEP, Catf1, RIPE3b1, Smbp-2, Smbp2, Smubp2, nmd, sma
Protein Interaction Partner: Gtf3c1, Hnrnph1, Ruvbl1, Abt1, Zbtb14, Tyr, Ighmbp2, Ruvbl2, Hspa1b, Slit3, Robo1,
Protein Size: 993 - 分子量
- 109 kDa
- 基因ID
- 20589
- NCBI登录号
- NM_009212, NP_033238
- UniProt
- P40694
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