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MITF 抗体 (Middle Region)

Name: MITF 抗体 (Middle Region)
SKU: ABIN2780334
Availability: OutOfStock

MITF 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 绵羊, 斑马鱼, 山羊 WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-MITF Antibody Titration: 0. (MITF 抗体 (Middle Region))

Host: Mouse Target Name: MITF Sample Tissue: Mouse Liver Antibody Dilution: 1ug/ml (MITF 抗体 (Middle Region))

2 images

(1 reference)

产品编号 ABIN2780334

发货至: 中国

Datasheet as PDF

抗原 See all MITF 抗体

MITF (Microphthalmia-Associated Transcription Factor (MITF))
抗原表位
19

15

13

9

8

7

7

7

4

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1
Middle Region
适用
116

63

24

16

5

4

4

4

3

3

3

2

2

2

2

2
人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 绵羊, 斑马鱼, 山羊
宿主
90

40

1

1
兔
Compatible Secondaries
克隆类型
83

49
多克隆
标记
63

10

4

4

4

4

4

4

4

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This MITF antibody is un-conjugated
应用范围
69

49

43

37

35

17

13

7

7

3

3

3

2

2

2

1

1

1
Western Blotting (WB)

序列

MGSKLEDILM DDTLSPVGVT DPLLSSVSPG ASKTSSRRSS MSMEETEHTC

预测反应

Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against MITF. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human MITF

Top Product

Discover our top product MITF Primary Antibody
anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 351-450) antibody
MITF 适用: 小鼠 WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) (pSer180), (pSer73) antibody
MITF 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) antibody
MITF 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-28), (N-Term) antibody
MITF 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB18810 unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) (Ser180), (Ser73) antibody
MITF 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-114) antibody
MITF 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 3A2E2 unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) antibody
MITF 适用: 人, 犬 IHC, IF, FACS, StM 宿主: 兔 Monoclonal MITF-2987R unconjugated Recombinant Antibody

anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-280) antibody
MITF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) (Ser180), (Ser73) antibody
MITF 适用: 人, 小鼠 WB, IHC, ELISA, IF/ICC 宿主: 兔 Polyclonal unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) antibody
MITF 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal D5 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 419 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Ursini, Cavalleri, Fazio, Angrisano, Iacovelli, Porcelli, Maddalena, Punzi, Mancini, Gelao, Romano, Masellis, Calabrese, Rampino, Taurisano, Di Giorgio, Keller, Tarantini, Sinibaldi, Quarto et al.: "BDNF rs6265 methylation and genotype interact on risk for schizophrenia. ..." in: Epigenetics, Vol. 11, Issue 1, pp. 11-23, (2016) (PubMed).
抗原

MITF (Microphthalmia-Associated Transcription Factor (MITF))

别名

MITF (MITF 产品)

别名

MITF antibody, ws2a antibody, mitfa antibody, MITF-A antibody, LOC100313655 antibody, mitfb antibody, CMM8 antibody, MI antibody, WS2 antibody, WS2A antibody, bHLHe32 antibody, BCC2 antibody, Bhlhe32 antibody, Gsfbcc2 antibody, Vitiligo antibody, Wh antibody, bw antibody, mi antibody, vit antibody, MITF-H antibody, MITF-M antibody, CMI9 antibody, melanogenesis associated transcription factor antibody, microphthalmia-associated transcription factor antibody, microphthalmia-associated transcription factor S homeolog antibody, Microphthalmia antibody, MITF antibody, mitf antibody, LOC100313655 antibody, mitf.S antibody, LOC100534525 antibody, MICROP antibody, Mitf antibody

背景

MITF is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: WS2A, MI, WS2, bHLHe32
Protein Interaction Partner: EBP, STUB1, HK3, EPAS1, LEF1, APP, HINT1, ELAVL1, CDK2, SUMO2, PSMD14, MARK3, PIAS3, PIAS2, PIAS1, SUMO1, UBE2I, PAX3, OTX2, PAX6, PATZ1, GSK3B, TFEC, EP300, RPS6KA1, TFEB, MAPK14, TFE3, MAPK1, SPI1, FOS, CTNNB1, CDKN1A, RB1,
Protein Size: 419

分子量

47 kDa

基因ID

4286

NCBI登录号

NM_000248, NP_000239

途径

Chromatin Binding