ZNF265 抗体 (N-Term)
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- 抗原 See all ZNF265 (Zranb2) 抗体
- ZNF265 (Zranb2) (Zinc Finger Protein 265 (Zranb2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZNF265 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RCGREKTTEA KMMKAGGTEI GKTLAEKSRG LFSANDWQCK TCSNVNWARR
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ZNF265. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF265
- Top Product
- Discover our top product Zranb2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 330 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Identification of the Zinc Finger Protein ZRANB2 as a Novel Maternal Lipopolysaccharide-binding Protein That Protects Embryos of Zebrafish against Gram-negative Bacterial Infections." in: The Journal of biological chemistry, Vol. 291, Issue 8, pp. 4019-34, (2016) (PubMed).
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Identification of the Zinc Finger Protein ZRANB2 as a Novel Maternal Lipopolysaccharide-binding Protein That Protects Embryos of Zebrafish against Gram-negative Bacterial Infections." in: The Journal of biological chemistry, Vol. 291, Issue 8, pp. 4019-34, (2016) (PubMed).
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- 抗原
- ZNF265 (Zranb2) (Zinc Finger Protein 265 (Zranb2))
- 别名
- ZNF265 (Zranb2 产品)
- 别名
- ZNF265 antibody, ZRANB2 antibody, c4sr antibody, zis antibody, zis1 antibody, zis2 antibody, znf265 antibody, zranb2 antibody, ZIS antibody, ZIS1 antibody, ZIS2 antibody, AI227013 antibody, Zfp265 antibody, Zis antibody, Znf265 antibody, zinc finger RANBP2-type containing 2 antibody, zinc finger RANBP2-type containing 2 L homeolog antibody, zinc finger, RAN-binding domain containing 2 antibody, ZRANB2 antibody, zranb2.L antibody, Zranb2 antibody
- 背景
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ZNF265 is a protein that has been shown to bind to the spliceosomal components U1-70K and U2AF35 and to direct alternative splicing. Analysis of the structure reveals substantial similarity to known RNA-binding motifs in terms of the distribution of key surface residues responsible for making RNA contacts, despite a complete lack of structural homology. An RNA gel shift assay was used to demonstrate that a single crossed finger domain from ZNF265 is capable of binding to an RNA message. Taken together, these results define a new RNA-binding motif and should provide insight into the functions of the >100 uncharacterized proteins in the sequence data bases that contain this domain.
Alias Symbols: ZIS, ZIS1, ZIS2, ZNF265
Protein Interaction Partner: UBC, C18orf25, TBC1D17, CORO1B, PARVA, SWAP70, OSBP, CDK1, FBXL7, SRPK2, SRPK1, CSNK2A1, KIF20A, SMURF1, UBE2B, UBA52, TYMS, TTC1, SULT1A1, SRSF7, PSMA1, PCMT1, UCHL3, UBE2V2, TTC9C, SRXN1, UNK, UBL7, ZNF644, UBQLN1, UBQLN2, UBXN7, TTLL12, UBE2C, AHCYL1,
Protein Size: 330 - 分子量
- 37 kDa
- 基因ID
- 9406
- NCBI登录号
- NM_203350, NP_976225
- UniProt
- Q5VV34
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