G3BP1 抗体 (N-Term)
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- 抗原 See all G3BP1 抗体
- G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 兔, Cow, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This G3BP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EVFGGFVTEP QEESEEEVEE PEERQQTPEV VPDDSGTFYD QAVVSNDMEE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against G3BP. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human G3BP
- Top Product
- Discover our top product G3BP1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 466 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Coxsackievirus counters the host innate immune response by blocking type III interferon expression." in: The Journal of general virology, Vol. 97, Issue 6, pp. 1-12, (2016) (PubMed).
: "Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication." in: Open biology, Vol. 6, Issue 7, (2016) (PubMed).
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Coxsackievirus counters the host innate immune response by blocking type III interferon expression." in: The Journal of general virology, Vol. 97, Issue 6, pp. 1-12, (2016) (PubMed).
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- 抗原
- G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
- 别名
- G3BP (G3BP1 产品)
- 别名
- G3BP antibody, HDH-VIII antibody, fj17h05 antibody, zgc:56034 antibody, wu:fj17h05 antibody, g3bp antibody, MGC53271 antibody, G3BP1 antibody, G3bp antibody, RGD1310666 antibody, AI849976 antibody, B430204O07 antibody, C87777 antibody, mKIAA4115 antibody, G3BP stress granule assembly factor 1 antibody, GTPase activating protein (SH3 domain) binding protein 1 antibody, GTPase activating protein (SH3 domain) binding protein 1 L homeolog antibody, Ras-GTPase-activating protein SH3-domain-binding protein antibody, G3BP1 antibody, g3bp1 antibody, g3bp1.L antibody, LOC100304885 antibody, G3bp1 antibody
- 背景
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G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: G3BP, HDH-VIII
Protein Interaction Partner: UBC, USP10, FXR2, MDM2, RNF2, BMI1, RPS27L, EDC4, RPL35, RPL14, EIF2B3, EIF3C, PTBP1, PIN1, PA2G4, YBX1, HNRNPU, FAU, SH3RF2, TARDBP, FBXO25, RIOK2, SND1, VCAM1, env, ITGA4, IL7R, FN1, EPHA8, DTX1, PABPC1, PAXIP1, ESR1, APP, NOLC1, TPM4, LCK, CSK, KCND3,
Protein Size: 466 - 分子量
- 51 kDa
- 基因ID
- 10146
- NCBI登录号
- NM_005754, NP_005745
- UniProt
- Q13283
- 途径
- SARS-CoV-2 Protein Interactome
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