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FXYD5 抗体 (N-Term)

FXYD5 适用: 人, 小鼠, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780210
发货至: 中国
  • 抗原 See all FXYD5 抗体
    FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, Saccharomyces cerevisiae
    宿主
    • 21
    • 1
    克隆类型
    • 22
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    This FXYD5 antibody is un-conjugated
    应用范围
    • 21
    • 16
    • 15
    • 2
    • 1
    Western Blotting (WB)
    序列
    LQPTSPTPTW PADETPQPQT QTQQLEGTDG PLVTDPETHK STKAAHPTDD
    预测反应
    Human: 100%, Mouse: 100%, Yeast: 90%
    产品特性
    This is a rabbit polyclonal antibody against FXYD5. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human FXYD5
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 178 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Song, Li, Sun, Zhao: "Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." in: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).

  • 抗原
    FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
    别名
    FXYD5 (FXYD5 产品)
    别名
    FXYD5 antibody, DYSAD antibody, IWU1 antibody, KCT1 antibody, OIT2 antibody, PRO6241 antibody, RIC antibody, EF-8 antibody, Oit2 antibody, FXYD domain containing ion transport regulator 5 antibody, FXYD domain-containing ion transport regulator 5 antibody, FXYD5 antibody, Fxyd5 antibody
    背景
    FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.
    Alias Symbols: RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241
    Protein Interaction Partner: UBC,
    Protein Size: 178
    分子量
    20 kDa
    基因ID
    53827
    NCBI登录号
    NM_144779, NP_659003
    UniProt
    Q96DB9
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