MAFA 抗体 (C-Term)
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- 抗原 See all MAFA 抗体
- MAFA (Transcription Factor MafA (MAFA))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAFA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KLEVGRLAKE RDLYKEKYEK LAGRGGPGGA GGAGFPREPS PAQAGPGAAK
- 预测反应
- Human: 86%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Mafa. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product MAFA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 359 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MAFA (Transcription Factor MafA (MAFA))
- 别名
- Mafa (MAFA 产品)
- 别名
- RIPE3b1 antibody, hMafA antibody, RGD1562627 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, SMaf1 antibody, mafl antibody, L-MAF antibody, MAFL antibody, Maf antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) antibody, MAF bZIP transcription factor A antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa antibody, monocyte to macrophage differentiation-associated antibody, Mafa antibody, MAFA antibody, Klrg1 antibody, mafa antibody, mafaa antibody, Mmd antibody
- 背景
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Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: RIPE3b1
Protein Interaction Partner: Psme3,
Protein Size: 359 - 分子量
- 37 kDa
- 基因ID
- 378435
- NCBI登录号
- NM_194350, NP_919331
- UniProt
- Q8CF90
- 途径
- Hormone Transport
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