电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

NMRAL1 抗体 (N-Term)

NMRAL1 适用: 大鼠, 小鼠, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780056
发货至: 中国
  • 抗原 See all NMRAL1 抗体
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    抗原表位
    • 8
    • 1
    • 1
    N-Term
    适用
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠, 小鼠, Cow, 犬, Pig
    宿主
    • 10
    • 2
    克隆类型
    • 12
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    This NMRAL1 antibody is un-conjugated
    应用范围
    • 7
    • 7
    • 2
    • 1
    Western Blotting (WB)
    序列
    GATGAQGGSV ARALLEDGTF RIRVVTRNPE QRAAKELKQQ GAEVVRGDQD
    预测反应
    Cow: 79%, Dog: 79%, Mouse: 100%, Pig: 86%, Rat: 86%
    产品特性
    This is a rabbit polyclonal antibody against Nmral1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the n terminal region of mouse Nmral1
    Top Product
    Discover our top product NMRAL1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 309 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    别名
    Nmral1 (NMRAL1 产品)
    别名
    HSCARG antibody, SDR48A1 antibody, 1110025F24Rik antibody, AI256624 antibody, RGD1311451 antibody, NmrA like redox sensor 1 antibody, NmrA-like family domain containing 1 antibody, NMRAL1 antibody, Nmral1 antibody
    背景
    Nmral1 is a redox sensor protein. Nmral1 undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP+ levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH.Nmral1 has higher affinity for NADPH than for NADP+. Binding to NADPH is necessary to form a stable dimer.
    Alias Symbols: 1110025F24Rik, AI256624
    Protein Size: 309
    分子量
    34 kDa
    基因ID
    67824
    NCBI登录号
    NM_026393, NP_080669
    UniProt
    Q8K2T1
You are here:
客服