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MCAF1 抗体 (Middle Region)

ATF7IP 适用: Pig, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780013
发货至: 中国
  • 抗原 See all MCAF1 (ATF7IP) 抗体
    MCAF1 (ATF7IP) (Activating Transcription Factor 7 Interacting Protein (ATF7IP))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Pig, 小鼠, 大鼠
    宿主
    • 6
    • 2
    克隆类型
    • 6
    • 2
    多克隆
    标记
    • 8
    This MCAF1 antibody is un-conjugated
    应用范围
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    MSTPEGEKSE KDGKAEEEER VPAEEQPPVR NEFSRRKRSK SEDMDSVESK
    预测反应
    Mouse: 100%, Pig: 92%, Rat: 85%
    产品特性
    This is a rabbit polyclonal antibody against Atf7ip. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of Mouse Atf7ip
    Top Product
    Discover our top product ATF7IP Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1306 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MCAF1 (ATF7IP) (Activating Transcription Factor 7 Interacting Protein (ATF7IP))
    别名
    Atf7ip (ATF7IP 产品)
    别名
    ATF7IP antibody, AM antibody, MCAF antibody, MCAF1 antibody, p621 antibody, 2610204M12Rik antibody, Mcaf1 antibody, fa12g02 antibody, wu:fa12g02 antibody, zgc:152981 antibody, activating transcription factor 7 interacting protein antibody, Atf7ip antibody, ATF7IP antibody, atf7ip antibody
    背景
    Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Atf7ip can both act as an activator or a repressor depending on the context. It mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Atf7ip is required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Atf7ip may have ATPase activity.
    Alias Symbols: 2610204M12Rik, AM, Mcaf1
    Protein Interaction Partner: Atf7, Gtf2f1, Gtf2e2, Aagab, Ccnh, Gtf2h1, Ercc3, Cdk7, C1qbp, POLR2H, POLR2G, POLR2D, POLR2C,
    Protein Size: 1306
    分子量
    138 kDa
    基因ID
    54343
    NCBI登录号
    NM_019426, NP_062299
    UniProt
    Q7TT18
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