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- 抗原 See all ATF4 抗体
- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
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抗原表位
- N-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATF4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MALFTKSSSS VAVTDKDTFE LSTFLESSKA PQHDRDELPE QRSVGGGLDD
- 预测反应
- Mouse: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ATF4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of mouse ATF4
- Top Product
- Discover our top product ATF4 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Antigen size: 381 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response." in: Antioxidants & redox signaling, (2016) (PubMed).
: "Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance." in: Cell, Vol. 155, Issue 1, pp. 172-87, (2013) (PubMed).
: "Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration." in: The Journal of clinical investigation, Vol. 123, Issue 10, pp. 4525-39, (2013) (PubMed).
: "Measurement of activation of the endoplasmic reticulum stress response in autoimmune myositis." in: Methods in enzymology, Vol. 489, pp. 207-25, (2011) (PubMed).
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Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response." in: Antioxidants & redox signaling, (2016) (PubMed).
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- 抗原
- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
- 别名
- ATF4 (ATF4 产品)
- 别名
- CREB-2 antibody, CREB2 antibody, TAXREB67 antibody, TXREB antibody, ATF4 antibody, atf-4 antibody, creb-2 antibody, creb2 antibody, taxreb67 antibody, txreb antibody, atf4 antibody, wu:fj01c08 antibody, wu:fk30b04 antibody, zgc:85951 antibody, sb:eu681 antibody, wu:fb08f07 antibody, zgc:171702 antibody, Atf-4 antibody, C/ATF antibody, ATF4-I antibody, atf4-a antibody, atf4-b antibody, atf4-ii antibody, activating transcription factor 4 antibody, activating transcription factor 4 L homeolog antibody, activating transcription factor 4a antibody, activating transcription factor 4b antibody, activating transcription factor 4 S homeolog antibody, ATF4 antibody, atf4 antibody, Atf4 antibody, atf4.L antibody, atf4a antibody, atf4b antibody, atf4.S antibody
- 背景
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Atf4 binds to asymmetric cAMP response elements (CRE) as a heterodimer and to palindromic CRE's as a homodimer.
Alias Symbols: Atf-4, C/ATF, CREB2, TAXREB67
Protein Interaction Partner: Egln3, Ubc, Hif1a, Satb2, Fam175b, Trib3, Gabbr2, Gabbr1, Jun, Fos, Dapk3, Rps6ka3, Tnfsf11, Prkaca,
Protein Size: 381 - 分子量
- 42 kDa
- 基因ID
- 11911
- NCBI登录号
- NM_009716, NP_033846
- UniProt
- Q61328
- 途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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